Caffeine is the most widely available legal psychoactive stimulant drug. Also known as theine, methyltheobromine and trimethylxanthine, this xanthine alkaloid is not only found in coffee beans, but also in guaranine that is derived from guarana, mateine derived from mate, theine which is found in various teas and the kola nut, which is the base flavor of various Cola soft drinks. It stimulates the central nervous system, where it restores alertness and wards off drowsiness. Caffeine is also know to display certain diuretic properties, is an ergogenic, an atagonist of the adenosine receptors, and a cAMP levels increasing factor. It seems that caffeine helps prevent the onset of Parkinson’s disease and in the long run lowers the possibility of developing a heart disease.

Chromium Polynicotinate is a product associated with medical food. It is used as a nutritional support in diabetes related conditions. Chromium polynicotinate is said to be nothing but an assimilated form of chromium. It is said to be the most effective type of chromium. It is absorbed by the body in its biologically active form. It is also crucial to the process of synthesis of fats, protein and cholesterol. Chromium polynicotinate if taken in monitored dosage can help stabilize blood sugar levels. This proves beneficial for people suffering from diabetes as well as hypoglycemia. Its main property is to produce insulin. Therefore, it helps in the metabolism of glucose. This type of chromium polynicotinate helps in the production of anabolic effects which have no side effects. On the other hand, they help in keeping the fat cells away from the muscle cells.

Cocoa Seed Extract is the extract of the seeds of Theobroma cacao. It is cultivated for its seeds which are present in its pod shaped fruits. The extracts from its seeds have a number of health benefits. They are also used to make chocolate. Studies show that Cocoa extracts contain a high level of flavonoids, specifically epicatechin, which may have beneficial cardiovascular effects on health. The ingestion of flavonol-rich cocoa is associated with acute elevation of circulating nitric oxide, enhanced flow-mediated vasodilatation, and augmented microcirculation. Researchers also found that consumption of Cocoa can reduce risk of cancer and can reduce elevated blood pressure.

Evodiamine, a bioactive alkaloid extract from the Evodiae Fructus plant, sometimes called Wu-Chu-Yu. Evodiamine is related to capsaicin, found in cayenne pepper. Evodiamine is a vanilloid receptor agonist, and may enhance lipolytic activity. Evodiamine has been shown to raise the body’s skin temperature and decrease core temperature, which is thought to burn calories and fat for energy.

Garcinia Cambogia is helpful for weight loss as it suppresses accumulation of body fats. It promotes fat oxidation, increases serotonin release and its availability in brain, normalizes lipid profiles and reduces serum leptin levels in overweight people. Garcinia cambogia extract improves mucosal defensive mechanisms in the stomach and, so, is a good protective agent against gastric ulcers. It reduces both the volume and acidity of gastric juice. It acts as an appetite suppressant and also enhances metabolism. Garcinia cambogia can be helpful for people who attempt to have a low carb diet. It helps improve energy levels and strengthen the immune system. Garcinia cambogia extract can increase mucosal defense means in stomach, thus helping with gastric ulcers. It can decrease stomach acidity, and increase defensive properties on gastric juices.

Ginger Root- Ginger is a very popular spice and has been used for culinary purposes for ages. Besides the widespread use in the cuisine of many nations, several traditional medicines, including the Indian and Chinese medicinal practices, have used this Zingiber officinale, as the Latin name goes, for its pain relieving, anti allergenic and anti inflammatory activities. Further uses have been noted for treatment of various ailments of the digestive tract, such as diarrhea and nausea, but also as general stomach settlers. While the use of the ginger root extract has been used in ginger beer and ginger ale beverages, the use as dietary supplement or component in nutritional supplement concoctions is relatively recent. The volatile oils of the ginger root extract have been noted for the antibacterial, analgesic, sedative and antipyretic properties.

Green Tea Extract- Camellia sinensis, or more commonly the tea plant is a genus of flowering plants which is generally being used to produce tea, including green tea, oolong, black tea, white tea and pu-erh tea, also called Bolay tea. The different oxidation process makes the final difference. Tea plants can grow out into a tree, but are generally pruned to allow for easy hand picking. While camellia sinensis is being cultivated all around the globe in tropical and subtropical regions, this South and Southeast Asian native is most popular when imported from India and China. Medical uses of tea stem from the traditional Chinese medicine, where it was used as a bronchodilator and to treat angina pectoris, coronary artery disease and peripheral vascular diseases. Green tea extract is used as appetite suppressant and thermogenesis increasing agent.

Guarana is not only a dietary supplement but also an energy booster as well as it has a high concentration of caffeine.

Hoodia Gordonii, which although popular, has no published randomized controlled trials in humans to show hoodia is safe or effective in pill form. One study published in the September 2004 issue of Brain Research found that injections of p57 (The Active ingredient in Raw, Fresh Cut Hoodia, not dried) into the appetite center of rat brains resulted in altered levels of ATP, an energy molecule that may affect hunger. The animals receiving the P57 injections also ate less than rats that received placebo injections. However, this was an animal study and INJECTIONS IN THE BRAIN are very different from oral consumption, so it cannot be used to show that oral hoodia can suppress appetite in humans. Hoodia Gordonii is a succulent (a cactus of the aloe family) found in the Kalahari desert of South Africa. Most Hoodia Gordonii products contain very little, if any of the active ingredient needed to suppress hunger. Real Hoodia is very rare and is even an endangered plant. Most importantly, Hoodia has only demonstrated any effect in fresh, raw pieces of the plant. The effectiveness of powdered Hoodia has yet to be shown and may actually increase hunger. It's main use is as a cheap alternative to the more expensive weight loss herbs, which are the only alternative left after the banning of ephedra. Most supplement manufacturers can not use the more expensive weight loss herbs because it will result in a product that would be too expensive to compete with other more popular inexpensive diet supplements.

Hordenine, which is found in many grassy plants and grains. Hordenine is related to tyramine and may stimulate the release of norepinephrine to produce a stimulant effect.

L-Tyrosine is a non-essential amino acid, which is used by the cells in order to synthesize the proteins and appears to help stabilize ones mood during periods of high stress levels.

Octopamine is related to noradrenaline. Octopamine was discovered by Vittorio Erspamer, an Italian scientist in 1948. Octopamine has a significant role in mollusks and is the central nervous system in snail. Octopamine also has a vital role in memory and learning in the fruit fly and honey bee. Octopamine is also useful for the firefly in releasing the light production. Octopamine mobilizes releasing fat in mammals and this has developed into promotion as a slimming aid on the internet. However, there is no apparent evidence about Octopamine facilitating weight loss. Octopamine also significantly increases the blood pressure in combination with stimulants such as weight loss supplements. This is extensively used in energy demanding insects such as spiders, lobsters, crabs and crayfish as their behaviors also include egg-laying, jumping and flying. Among vertebrates, Octopamine substitutes norepinephrine and as well exhibits common side effects. Octopamine is sited in the locust jump such that it modulates the muscle activity allowing the leg muscles to contract effectively.

Pantothenic Acid, commonly called vitamin B5, is water soluble and is needed by every cell in the body to maintain good health. It helps in breaking down carbohydrates, fats and proteins to provide the body with energy. It assists in the production of red blood cells and hormones and ensures a healthy pregnancy. It is also known to lower triglyceride and cholesterol levels in the body. It helps in reducing stress and treating people with rheumatoid arthritis. Pantothenic acid is found in small quantities in almost all foods but abundantly in meats, fish, poultry, avocados, peas, broccoli and whole grains. A deficiency which is rare, leads to leg cramps, gastrointestinal problems, anemia, insomnia, depression, a burning sensation in the limbs and a weakened immune system.

Synephrine is an active compound that may be found in the fruit called Citrus aurantium or Zhi Shi in Chinese. Its chemical composition is similar to ephedrine and pseudo-ephedrine that may be found in most over the counter cold or allergy medications, weight loss and energy supplements. Unlike ephedrine, Synephrine is considered to be semi-selective sympathomimetic that targets tissues such as fats instead of the heart. It also helps the metabolism without the negative effects of ephedrine to the nervous system. It also increases the energy level, helps the body burn fat and promotes weight loss. It also aids the body to increase the quickness of caloric expenditure.

Vinpocetine- The lesser periwinkle plant named Vinca Minore consists of Vincamine, which is found in its leaves and Vinpocetine is derived from this natural substance found in the plant. In countries such as Japan and Europe, Vinpocetine is a prescribed medicine. It is popularly available in the online stores and countries such as Canada and the US as an effective supplement for diet. Vinpocetine is a great medicine in order to protect oneself from brain dementia. It has also been found to help treat Alzheimer’s disease. However, there is no strong recent evidence to prove its effect on the treatment of Alzheimer’s disease. Overall, it’s great to boost the brain. However, it has certain side effects such as anxiety, insomnia, indigestion, dry mouth, headache and many more.

White Willow Bark is used as an anti-inflammatory and treats pains such as joint pain, flu, fever, back pain and osteoarthritis.

Yerba Matte is believed to possess cancer-fighting properties and has shown to have a relaxing effect on muscle tissues and a stimulating effect on heart tissues.