17-dihydroxy-delta-5-etiocholane-7-one diethylcarbonate, also known as A7-E is billed as a thyroid “super charger”. It is a powerful fat-loss agent that melts away the fat while leaving the muscle. This supplement boosts T-3 while not suppressing TSH. It is a combination of the compounds 3, 17-dihydroxy-delta-5-etiocholane 7-one also known as A7-D and guggulsterones. A7-D increases the T3 levels but does not suppress TSH. Guggulsterones increase the conversion of T4 into T3. The thyroid only produces about 20% of the bodies T3 the remaining 80% is made up from T4. Now, because the bioavailability is low and the active life span is short A7-D was turned into a carbonate ester giving us A7-E.

9-Carbonate is a compound which gives out carbon-dioxide when mixed with acid. Our body cannot digest large amounts of carbon-dioxide, when we sip carbonated beverages carbon dioxide gets pumped into the body and irritates the stomach. Since it is extremely acidic and unnatural our body tries to rectify it secreting an antacid of calcium by absorbing it from the blood. The more carbonated beverages you consume the more the production of calcium by the stomach, resulting in depletion of body nutrients. As the calcium from the blood begins to decrease and calcium gets absorbed from the bones, it eventually makes the bones weak and brittle. Consuming carbon-dioxide in excess amounts exposes you to many potential dangers like acid reflux, cell damage, cancer and loss of calcium

Caffeine is of course a major component of every day drinks such as tea and coffee and is also included in Hot-Rox Extreme. It is claimed that over 70% of the American population take more than 300 milligrams daily. As well as in familiar drinks it is used in energy drinks such as Red Bull as well as in many over the counter analgesics and other medication. Medically it is a as trimethylxanthine, useful as a heart stimulant and it also works as a mild diuretic. It works in the same way as certain drugs, the amphetamines, cocaine, and heroin, all of which work on the action of the brain although in a milder way, and like them it is addictive.

Forskolin- the compound Forskolin comes from Coleus forskohlii, a plant that has been used in Hindu and Ayurvedic medicine for ages. Today, Forskolin is being extensively used in most advanced thermogenics and fat burners due its unique biological importance. Forskolin plays a vital role in weight loss owing to its natural fat-loss enhancing properties and also helps in maintaining healthy blood pressure levels, which are already in the normal range. It is a known fact that our body's metabolism depends on the hormones that are released by the thyroid and Forskolin boosts the production of these hormones. It also stimulates thyroid hormone release so as to increase the metabolic rate of the body further. Forskolin also offers various other health benefits due to its effect on cyclic adenosine monophosphate (cAMP), an important cell regulating compound.

Lauroyl Macrogol-32 Glycerides~

Piperine, an extract that comes from the fruit of the black pepper plant “Piper Nigrum” and “Piper Longum,” sets the stage for the activities in the body that lead to digestion and intestinal absportion by increasing the metabolic process. It is a pungent substance that has been used in Ayurvedic medicine for treatment of various diseases and is commercially available. Piperine forms monochenic needles, is slightly soluble in water and even more so in alcohol, ether, or chloroform. It significantly enhances the body’s ability to absorb nutrients into the blood stream, and supports the body’s natural thermogenic activities. It inhibits human CYP3A4 and P-glycoprotein, which are enzymes that are important for transport of xenobiotics and metabolites. Piperin has been found to stimulate skin pigmentation when exposed to UVB light. Caution should be used by those on other medications if taking this extract because of piperin’s effects on drug metabolism.

Yohimbine HCL, sometimes called yohimbine hydrochloride, yohimbe, or yohimbe bark, is an herbal supplement which serves as a stimulant and possible aphrodisiac for users. Yohimbine has also been shown to be successful in treating erectile dysfunction and impotence in men. It may serve to boost the sex drive of those who take it for aphrodisiac purposes. Some people are recommended to take yohimbine to combat their lower sex drives caused by antidepressants. Yohimbine has also been shown to help blood pressure levels and assist in weight loss. For these reasons, yohimbine is a popular supplement amongst athletes as well as many others wishing to improve their health.