17-dihydroxy-delta-5-etiocholane-7-one diethylcarbonate, also known as A7-E is billed as a thyroid “super charger”. It is a powerful fat-loss agent that melts away the fat while leaving the muscle. This supplement boosts T-3 while not suppressing TSH. It is a combination of the compounds 3, 17-dihydroxy-delta-5-etiocholane 7-one also known as A7-D and guggulsterones. A7-D increases the T3 levels but does not suppress TSH. Guggulsterones increase the conversion of T4 into T3. The thyroid only produces about 20% of the bodies T3 the remaining 80% is made up from T4. Now, because the bioavailability is low and the active life span is short A7-D was turned into a carbonate ester giving us A7-E.

9-Carbonate is a compound which gives out carbon-dioxide when mixed with acid. Our body cannot digest large amounts of carbon-dioxide, when we sip carbonated beverages carbon dioxide gets pumped into the body and irritates the stomach. Since it is extremely acidic and unnatural our body tries to rectify it secreting an antacid of calcium by absorbing it from the blood. The more carbonated beverages you consume the more the production of calcium by the stomach, resulting in depletion of body nutrients. As the calcium from the blood begins to decrease and calcium gets absorbed from the bones, it eventually makes the bones weak and brittle. Consuming carbon-dioxide in excess amounts exposes you to many potential dangers like acid reflux, cell damage, cancer and loss of calcium

Caffeine is the most widely used legal stimulant of the central nervous system and is also used in Hot-Rox Extreme, with characteristics that have been described as restoration of alertness and removing from drowsiness. Coffee, Tea, many soft drinks and energy drinks as well as nutrition supplements have this ingredient, which is a psychoactive substance, a xanthine alkaloid that can act as a adenosine receptor antagonist, as well as a phosphodiesterase inhibitor. Although regular use of caffeine seems to have nootropic effects, enhancing cognitive abilities, it also is known to provide long term effects on the nervous and cardiovascular system, like in one study it was proven that people with normal to low blood pressure have the possibility of developing a heart disease significantly reduced, as well as the chance of getting the Parkinson’s disease.

Forskolin- the compound Forskolin comes from Coleus forskohlii, a plant that has been used in Hindu and Ayurvedic medicine for ages. Today, Forskolin is being extensively used in most advanced thermogenics and fat burners due its unique biological importance. Forskolin plays a vital role in weight loss owing to its natural fat-loss enhancing properties and also helps in maintaining healthy blood pressure levels, which are already in the normal range. It is a known fact that our body's metabolism depends on the hormones that are released by the thyroid and Forskolin boosts the production of these hormones. It also stimulates thyroid hormone release so as to increase the metabolic rate of the body further. Forskolin also offers various other health benefits due to its effect on cyclic adenosine monophosphate (cAMP), an important cell regulating compound.

Lauroyl Macrogol-32 Glycerides~

Piperine a pungent substance that is found in plants of Piperaceae family, increases the strength of several supplements and drugs. It enhances thermal energy mass on a molecular cellular basis by raising energy supply, which as a result increases metabolic processes. This pathway causes increased demand for additional nutrients and energy, necessary for efficiency of metabolism. Piperine considerably increases absorption of nutrients into blood stream. It enhances the body's thermogenic activity that is directly related to the process of generating energy in the cells. It is also helpful in enhancing brain’s production of beta-endorphins and serotonin. Piperine decreases production of acid and ulceration of stomach. It also helps ease pain.

Yohimbine HCL is the active chemical component of the medicinal herb Pausinystalia yohimbe. It is a stimulant drug and is reportedly an aphrodisiac. According to the National Institute of Health (NIH), the standardised form of this chemical is Yohimbine hydrochloride (HCL) and is available as a prescription drug in the United States. Research has shown that yohimbine hydrochloride is effective as a treatment for male impotence. However while yohimbine HCL has been used as a prescription medicine to treat erectile dysfunction controlled studies suggests conflicting results. Apart from male sexual dysfunction, yohimbine HCL has also been used to treat the side effects of antidepressants like female hyposexual disorder etc. It is also used to recall memories in the treatment of post-traumatic-stress-disorder. While there are several uses for yohimbine HCL, there are several side effects too. These include high blood pressure, insomnia, panic attacks, hallucinations, headaches, renal failure, heart disease etc.